Zavod za Molekularnu medicinu i biotehnologiju

Novosti

Seminarske teme


S1 MATIČNE STANICE

S1.1. Uvod u matične stanice
Cloning and embryonic stem cells (Solter, CMJ)
Nature 2011 Flexible friends
Trent - Molecular Medicine

S1.2. Embrionalne matične stanice
Human embryonic stem cells
Nature 2008 in search
Never say die
From teratocarcinomas to embryonic stem (Soter, Nature 2006)

S1.3. Matične stanice u odraslom organizmu
The right neighbour
Epigenetic regulation of aging (Oncogene 2011)
Tracking adult stem cells (EMBO)

S1.4. Inducirane pluripotentne matične stanice
Induction of pluripotent stem cells (Celll, 2007)
iPS Nature review 2012


S2 STANIČNA TERAPIJA

S2.1. Stanična terapija - bolest 1
Cell therapy for spinal cord injury 2010

S2.2. Stanična terapija - bolest 2
Cardiac 2010
Cardiac Lancet 2011

S2.3. Stanična terapija - bolest 3
Dijabetes (EMBO 2011)

S2.4. Stanična terapija - bolest 4
Stroke 2010


S3 KLONIRANJE SISAVACA

S3.1. Kloniranje sisavaca - uvod i metode
S3.2. Problemi kod kloniranja
S3.3. Terapijsko i reproduktivno kloniranje
Kloniranje sisavaca (Solter, CMJ)
Solter 2000 Mammalian cloning
Trent - Molecular Medicine


S4 HUMANI GENOM

S4.1. Humani genom - uvod
Initial sequencing and analysis of the human genome (Nature 2001)
Finishing the euchromatic sequence of the human genome

S4.2. Humani genom - danas
R Gray 2000 SNP
SNP in general review (PLOS 2006)
Science after the sequence (Nature 2010)

S4.3. Humani genom i bolesti
SNP and autism genetics 2009 review
SNP and cancer review 2009
SNP in p53 pathway 2007 review


S5 HUMANA MOLEKULARNA GENETIKA

S5.1. Humana molekularna genetika - uvod
Finding the missing heritability review 2009
Discovering genotypes underlying human phenotypes (Nature)

S5.2. Humana molekularna genetika - monogenske bolesti
Cystic fibrosis (NEJM 2005 review)
Cystic fibrosis screening (NEJM)
Hemofilija (NEJM review)

S5.3. Humana molekularna genetika - poligenske bolesti
Shizofrenija
Type 1 diabetes mellitus


S6 GENSKA TERAPIJA

S6.1. Genska terapija - uvod
Gene therapy 2004
Gene Therapy progress 2005
GeneTherapyFS27

S6.2. Adenovirusi
Viral vectors for gene therapy (Nature 2001)

S6.3. Adeno associated virusi
Viral vectors for gene therapy (Nature 2001)
AAV vectors and tumorigenicity

S6.4. Retrovirusi
Viral vectors for gene therapy (Nature 2001)
Retroviral Safety Issues Curr Gene Th. 2005

S6.5. Genska terapija za bolest 1
Haemophilia B Gene therapy (NJM Dec 2011)
Merry Christmas for haemophilia B (Dec 2011)

S6.6. Genska terapija za bolest 2
Cistična fibroza
Cistična fibroza 2

S6.7. Genska terapija za bolest 3
Live and let die (Molecular Therapy Jan 2012)


S7 TRANSGENIČNE ŽIVOTINJE

S7.1. Transgenične životinje - uvod
Trangenic animal production and biotechnology, overview 2007
Progress in gene transfer 2008

S7.2. Transgenične životinje u istraživanju: kondicionalni knock-out
Conditional gene inactivation using Cre (2002)
Conditional gene targeting (Rajewsky, 1996)
Sauer Cre_LoxP (1998)

S7.3. Transgenične životinje u biotehnologiji
Transgenic animals in use
Transgenic swine for biomedicine and agriculture (2003)
Production of transgenic livestock: Promise fulfilled


S8 TRANSGENIČNE BILJKE

S8.1. Transgenične biljke - uvod: način proizvodnje
Agrobacterium review (2006)
Agrobacterium is not alone review (2006)
Genetically modified myths and realities review (2010)
http://www.biotechnology4u.com/plant_biotechnology_gene_transfermethods_plants.html

S8.2. Transgenične biljke - najčešće GM biljke
http://www.gmo-compass.org/eng/home/

S8.3. Transgenične biljke i okoliš
Does the use of transgenic plants diminish or promote biodiversity (2010)
Keeping the genie in the bottle review (2009)
Will transgenic plants affect the environment review (2005)

S8.4. Transgenične biljke - primjena u proizvodnji vakcina
Plant based vaccines for potential human application review (2009)
Plants as bioreactors review (2009)

S8.5. Transgenične biljke - druge primjene i budućnost
Transgenic plants for phytoremediation of herbicides
Transgenic plants phytoremediation of xenobiotics review (2009)


S9 REKOMBINANTNI PROIZVODI

S9.1. Rekombinantni proizvodi - uvod (sistemi za proizvodnju)
Recombinant protein production (2009 review)

S9.2. Primjeri rekombinantnih proizvoda u primjeni 1
Manufactoring challenges factor VIII review (2002)
Factor VIII safety

S9.3. Primjeri rekombinantnih proizvoda u primjeni 2
Darbopoetin coming of age (2007)
Development of NESP (2001)
Expression systems for glyc.
Huh-7 cell line (Paper JTM)


S10 VAKCINE

S10.1. Vakcine - uvod, klasična i nova cjepiva
Tipovi vakcina
The real issues in vaccinology
The case of measles
Target the fence
Lessons from polio

S10.2. Vakcine - trendovi danas 1
DNA vaccines (2010)
Designa and production of recombinant subunit vaccines

S10.3. Vakcine - trendovi danas 2
T-cell inducing vaccines (2012)
HIV vaccinology persistence pays off
A 2020 vision
Cancer vaccines overview (2009)


S11 MOLEKULARNA DIJAGNOSTIKA 1

S11.1 Molekularna dijagnostika - proteini (principi)
Monoclonal vs polyclonal antibodies

S11.2. Protutijela - monoklonska i poliklonska
Monoclonal vs polyclonal antibodies


S12 MOLEKULARNA DIJAGNOSTIKA 2

S12.1. Molekularna dijagnostika - nukleinske kiseline (principi)
DNA diagnostic

S12.2. Što i kako se dokazuje na Zavodu
Istražiti


S13 MEHANIZMI DJELOVANJA LIJEKOVA

S13.1. Lijek 1
Imatinib

S13.2. Lijek 2
Herceptin

S13.3. Lijek 3
Monoclonal antibodies

S13.4. Lijek 4
CdK inhibitor


S14 BUDUĆNOST MOLEKULARNE MEDICINE

S14.1. Budućnost 1
Cancer stem cells: old concepts, new insights (2008)

S14.2. Budućnost 2
Personalized medicine

S14.3. Budućnost 3
MicroRNA
MicroRNA therapeutics

S14.4. Budućnost 4
Nanomedicine in cancer therapy
objavljeno 22 03 2012

 

 

 

 

 

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